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Formulation and characterization of LNP LNP was generally comprised of 4 lipid components, i.e., ionizable lipid D-Lin-MC3-DMA (MCE, NJ, USA), distearoylphosphatidylcholine (DSPC), cholesterol and DMG-PEG 2k (Millipore Sigma, St

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In addition, iFSP1 was shown to inhibit FSP1 in a species-dependent manner, revealing structural features that confer selectivity for the human enzyme 120

254,255 Keap1/Nrf2/ARE signaling pathways As mentioned, the NF-B, MAPK, and JAK-STAT (signal transducers and activators of transcription) signaling pathways are involved in the development of inflammation